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1 - - Vol 27, No.1, 2024
- Chin J Dent Res 2024;27(1):17–28; doi:10.3290/j.cjdr.b5136791
- The Role of DSPP in Dentine Formation and Hereditary Dentine Defects
- Jie JIA, Zhuan BIAN, Yaling SONG
- The dentine sialophosphoprotein (DSPP) gene is the only identified causative gene for dentinogenesis imperfecta type 2 (DGI-II), dentinogenesis imperfecta type 3 (DGI-III) and dentine dysplasia type 2 (DD-II). These three disorders may have similar molecular mechanisms involved in bridging the DSPP mutations and the resulting abnormal dentine mineralisation. The DSPP encoding proteins DSP (dentine sialoprotein) and DPP (dentine phosphoprotein) are positive regulators of dentine formation and perform a function during dentinogenesis. The present review focused on the recent findings and viewpoints regarding the relationship between DSPP and dentinogenesis as well as mineralisation from multiple perspectives, involving studies relating to spatial structure and tissue localisation of DSPP, DSP and DPP, the biochemical characteristics and biological function of these molecules, and the causative role of the proteins in phenotypes of the knockout mouse model and in hereditary dentine defects.
  
  Key words: dentine mineralisation, dentine sialophosphoprotein, hereditary dentine defects, mutation
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- Chin J Dent Res 2024;27(1):13–15; doi:10.3290/j.cjdr.b5139351
- Wearing Sports Mouthguards to Prevent Oral and Maxillofacial Trauma
- Chinese Stomatological Association
- The theme of the academic annual conferences held by the Chinese Stomatological Association from 2021 to 2023 was “Protecting Natural Teeth to Maintain Oral Health” and coincided with the 24th Winter Olympic Games that took place in Beijing in 2022, and thus prevention of oral and maxillofacial trauma once again attracted the attention of stomatological experts and the public. The incidence of oral and maxillofacial trauma caused by sports is around 25% to 34%1-5, and varies based on the type of sport and other factors, such as age, sex and the skill level of the participants. The risk of oral and maxillofacial trauma is extremely high in high-confrontation and high-speed sports, especially for children and adolescents. Wearing sports mouthguards when participating in sport is an effective way to prevent and reduce the incidence of oral and maxillofacial trauma in such sports, and is the simplest and most practical method of doing so. Sports have developed and gained in popularity significantly in China in recent years, but the awareness and use of sports mouthguards are low. Based on the above background, the Chinese Stomatological Association advocates that athletes and sport participants should wear mouthguards in various confrontational and high-speed sports, and calls on dental practitioners and sports-related organisations to actively support the popularisation and application of sports mouthguards to prevent or alleviate oral and maxillofacial trauma and to raise awareness and increase knowledge of methods to protect natural teeth.
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- Chin J Dent Res 2024;27(1):11–12; doi:10.3290/j.cjdr.b5139365
- Preserving Natural Teeth to Maintain Oral Health
- Chinese Stomatological Association
- Oral health is an important component of general health, and oral disease is one of the most common human diseases that not only affects oral health and quality of life, but is also closely associated with overall health. Natural teeth are important functional organs and are crucial to oral functions and maintaining a healthy life. The Chinese Stomatological Association (CSA) has released this position statement on “Preserving Natural Teeth to Maintain Oral Health”, which is one of the most important achievements of the 2021 to 2023 CSA Annual Congress themed “Healthy Mouth, Protecting Natural Teeth”, advocating that everyone should take effective measures to protect their natural teeth, maintain oral health and promote general health.
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